The study investigated how the robots – 'Magnetically Aligned Nanorods In Alginate CapsuleS' (aka ‘Maniacs’) – could perform as drug delivery vehicles inside the body. It found that, when controlled using a magnetic field, the robots can move against fluid flow, climb slopes and move through neural tissue, such as the spinal cord, to deposit substances at precise locations.
Disease in the central nervous system can be very difficult to treat. Lamar Mair of Weinberg Medical Physics, which partnered with the academics on the study, explained: “Delivering drugs orally or intravenously, for example, to target cancers or neurologic diseases, may affect regions of the body and nervous system that are unrelated to the disease. Targeted drug delivery may lead to improved efficacy and reduced side-effects due to lower off-target dosing.”
One way to target dosing is to use tiny robots which enter the body to deliver drugs to specific locations; a technology...