It is estimated that around 1.5 million people die every year around the world due to a lack of effective vaccines, with many more suffering the side effects of avoidable diseases.
Vaccines work by training the immune system to recognise and respond to infection with a specific pathogen, such as a virus, parasite or bacteria. At the heart of every vaccine is an antigen - a small, safe molecule based on part of the pathogen, which triggers the protective immune response.
Most vaccine antigens are based on a single pathogen component, such as the spike protein in Covid-19, or the coat protein of the malaria parasite, which limits their effectiveness and ability to cope with new variants.
Baseimmune has developed a new vaccine design algorithm that is capable of creating new synthetic antigens containing all the parts of the pathogen that are most likely to evoke a strong protective immune response.
These ‘pick and mix’ antigens effectively present the immune...