Cancer drugs to be tested in orbit during space mission
The cells were launched into the International Space Station (ISS) via the second Axiom Space Private Astronaut Mission, Axiom Mission 2 (Ax-2) . The experiments, conducted by a team at the University of California San Diego Sanford Stem Cell Institute, aim to expand the scientists' understanding of human stem cell ageing, inflammation and cancer in low-Earth orbit. During the first Axiom Mission, in 2021, the team discovered that cancer stem cells regenerate more easily and become more resistant to standard therapies in low-Earth orbit, due to the microgravity conditions. Two enzymes that edit DNA and RNA ( APOBEC3C and ADAR1) were found to activate themselves in a significant way during space stays, increasing cancer proliferation and immune evasion. In this new mission, the team…